email forum - by joining the group e-mail forum you will be in contact with Alpha patients, their families, carers and friends living throughout the UK and overseas. We are a friendly group, and between us we have a wealth of knowledge and experience to share. There is always someone to help with any worries or queries you might have.

What is Alpha-1 Antitrypsin Deficiency?

Alpha-1 Antitrypsin Deficiency also known as Alpha-1, A1AD or AATD is an inherited, genetic condition that is passed on from generation to generation. As the name suggests it is a deficiency of alpha-1 antitrypsin (AAT) in the bloodstream. AAT is an enzyme produced in the liver to help protect the tissues of the body during infections. The low level of AAT in the blood occurs because the AAT is abnormal and cannot be released from the liver at the normal rate. This leads to a build up of abnormal AAT in the liver that can cause liver disease and a decrease of AAT in the blood that can lead to lung disease.

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Annual Social Gathering

Alpha-1 UK Support Group
13th Annual Social Gathering and Information Day
Bentley Hotel Leisure Club and Spa
Newark Road, South Hykeham, Lincoln LN6 9NH
Saturday 20th September 2014

Our Annual Social Gathering and Information Day which this year is in the historic city of Lincoln is fast approaching. The event is one of the largest gatherings of Alphas and their families in the UK where you can meet and socialise with fellow Alphas and be updated by leading experts in the field of Alpha-1 Antitrypsin Deficiency.

It is a great time to catch up with old friends and meet new, it helps to put faces to names and gives you the opportunity to talk to many others who are in the same situation as you. The day is very informal and EVERYONE is welcome, wife's, partners, husbands, children, family members and any friends who might be interested, so if you have not yet booked your main contact for registration, hotel rooms etc is:

John L Mugford -
More Information


To request a free Alpha-1 Information Pack or Booklets and Posters for your GP Surgery and Hospital please e-mail us with your full name and address.
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