email forum - by joining the group e-mail forum you will be in contact with Alpha patients, their families, carers and friends living throughout the UK and overseas. We are a friendly group, and between us we have a wealth of knowledge and experience to share. There is always someone to help with any worries or queries you might have.

What is Alpha-1 Antitrypsin Deficiency?

Alpha-1 Antitrypsin Deficiency also known as Alpha-1, A1AD or AATD is an inherited, genetic condition that is passed on from generation to generation. As the name suggests it is a deficiency of alpha-1 antitrypsin (AAT) in the bloodstream. AAT is an enzyme produced in the liver to help protect the tissues of the body during infections. The low level of AAT in the blood occurs because the AAT is abnormal and cannot be released from the liver at the normal rate. This leads to a build up of abnormal AAT in the liver that can cause liver disease and a decrease of AAT in the blood that can lead to lung disease.


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Latest News

Cabinet Health Secretary commits to improving care...
24 Nov 2014 15:50

In a landmark seminar at the Scottish Parliament last week, the Alpha-1 Alliance moved one step closer to achieving its goal of improving health services for patients of the condition in Scotland –  [ ... ]

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Policy Report On Alpha-1 Care Scotland Published
04 Nov 2014 16:03

The Alpha-1 Alliance today released its policy report on the current level of care for Alpha-1 patients in Scotland.

The report draws upon the findings of a survey of Scottish Alpha-1 patients, relativ [ ... ]

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Alpha-1 Researcher Maurizio Luisetti Passes Away
23 Oct 2014 19:21

Prominent Alpha-1 researcher Maurizio Luisetti, MD, of Pavia, Italy, passed away on Monday, Oct. 20, after a brief illness. He was 61 years old. “We have lost a dear friend and pioneer in Alpha-1 [ ... ]

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Scottish Alpha-1 patients – the campaign needs you...
01 Oct 2014 16:27

Alpha-1 Alliance hosts seminar on Alpha-1 at the Scottish Parliament on 19th November The Alpha-1 Alliance warmly invites Scottish Alpha-1 patients and their family members to attend our Parliamen [ ... ]

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Highland Climber Signs Up In Capital
15 Sep 2014 09:59

A Highland mother-of-five with just 24% lung capacity has climbed a steep rock face at Edinburgh Castle to place a huge Yes sign in full view of thousands of people.

Climber Lindsay Jarrett, 42, of Kin [ ... ]

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Government Consider Alpha-1 NHS national service
03 Sep 2014 09:13

Government committee to consider Alliance application for Alpha-1 NHS national service The establishment of an NHS national service for the treatment of Alpha-1 could move a step closer this month wh [ ... ]

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